Cooperation between C/EBP(alpha) TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation

Article Abstract:

Research has been conducted on the chromatin remodeling important for the promoter activation during cellular lineage commitment and differentiation. The ability of the C/EBP(alpha) transcription factor to direct adipocyte uncommitted fibroblast precursor differentiation and to activate the SWI/SNF-dependent myeloid-specific genes has been investigated and the results are reported.

Denmark, Germany, Statistical Data Included, Fibroblasts, Fat cells, Adipocytes

Histone H3 tail positioning and acetylation by the c-Myb but not the v-Myb DNA-binding SANT domain

Article Abstract:

The binding of c-Myb-DNA-binding domain (DBD) to the N-terminal histone tails of H3 and H3.3 is discussed. A function in chromatin organization is displayed by Myb by directing the modifications of histone through its SANT-DBD.

Science & research, Research, Histones, DNA-ligand interactions, DNA binding

Heterochromatin: stable and unstable invasion at home and abroad

Article Abstract:

The authors discusses the studies on heterochromatin. The topics of interest include the analysis of different types of heterochromatin and heterochomatin invasion into euchromatin.

United States, Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, DNA, Genomes