Global carbon utilization profiles of wild-type, mutant, and transformant strains of Hypocrea jecorina

Article Abstract:

A study was conducted to investigate the global carbon metabolism of Hypocera jecorina per se and to compare it to genetically modified strains obtained after classical mutagenesis or DNA-mediated transformation. The data obtained demonstrate that the wild-type isolates and transformed strains had the highest variation in growth patterns on individual carbon sources and cellulase mutants were relatively similar to their parental strains.

author: Kubicek, Christian P., Seiboth, Bernhard, Druzhinina, Irina S., Schmoll, Monika
Genetic aspects, Mutagenesis, Ascomycota, Biological oxidation (Metabolism)

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Application of DNA bar codes for screening of industrially important fungi: the haplotype of Trichoderma harzianum sensu stricto indicates superior chitinase formation

Article Abstract:

Chitinase production by Hypocrea lixii/Trichoderma harzianum is used as a model for testing whether fungal strains with superior enzyme formation are diagnosed by DNA bar codes. The analysis has shown that Trichoderma harzianum strains having one specific haplotype has displayed statistically supported superior chitinase production and that this haplotype is differentiated by DNA bar codes for at least two phylogenetic markers.

author: Kubicek, Christian P., Druzhinina, Irina S., Nagy, Viviana;, Seidl, Verena, Szakacs, George, Komon-Zelazowska, Monika
Physiological aspects, Chitin, Genetic markers, Chemical properties, DNA microarrays

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Role of the bga1-encoded extracellular beta-galactosidase of hypocrea jecorina in cellulase induction by lactose

Article Abstract:

The role of the major beta-galactosidase of Hypocrea jecorina in lactose metabolism and cellulase induction is investigated. It is concluded that cellulase, production on lactose occurs when beta-galactosidase activity levels are low but decreases as the beta-galactosidase activities increase.

author: Kubicek, Christian P., Seiboth, Bernhard, Hartl, Lukas, Salovuori, Noora, Lanthaler, Karin, Robson, Geoff D., Vehmaanpera, Jari, Penttila, Merja E.
Metabolism, Lactose

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subjects list: Research, Fungi