Metabolism of benzonitrile and butyronitrile by Klebsiella pneumoniae

Article Abstract:

The metabolism of a Klebsiella pneumonia strain which utilizes benzonitriles as the sole carbon and nitrogen source was investigated. Results showed that strain NCTR degraded both benzoic acid and ammonia. The isolate also metabolized butynitrile to ammonia butyramide. Furthermore, K. pneumonia utilized aliphatic nitriles such as benzamide, butyramide, benzoic acid and butyric acid as sources of nitrogen.

author: Cerniglia, Carl E., Heinze, Thomas M., Nawaz, Mohamed S.
Klebsiella, Nitrogen metabolism, Nitriles

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Reduction of malachite green to leucomalachite green by intestinal bacteria

Article Abstract:

A study was conducted on the metabolization of malachite green to leucomalachite green by bacteria in human gastrointestinal tracts. Intestinal bacteria studied include 14 pure cultures of anaerobic bacteria and intestinal microfloras from rat, monkey, mouse and human fecal samples. Results reveal how intestinal microflora influences triphenylmethane dye metabolic activation to carcinogens.

author: Cerniglia, Carl E., Heinze, Thomas M., Henderson, Allison L., Schmitt, Thomas C.
Bacteria, Gastrointestinal diseases, Leukocytes, White blood cells

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Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora

Article Abstract:

The anaerobic metabolic studies of human intestinal bacteria that reduce Sudan dyes to form potentially carcinogenic aromatic amines are demonstrated.

author: Cerniglia, Carl E., Heinze, Thomas M., Haiyan Xu, Siwei Chen, Huizhong Chen
Science & research, Cyclic crudes and intermediates, Azoic Dyes & Components, Synthetic Organic Dye and Pigment Manufacturing, Intestines, Intestinal microbiology, Metabolism, Cocarcinogens, Carcinogens, Azo dyes, Chemical properties

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subjects list: Research