Microbial responses to microgravity and other low-shear environments

Article Abstract:

The potential future research trends aimed at understanding the effect of changes in mechanical forces that occur in microgravity and other low-shear environments on different microbial parameters. The response of microbes to changes in mechanical and physical forces is analyzed that is proposed to provide insight into a key mechanism to orchestrate and fine-tune the cellular response to environmental stimuli.

author: Wilson, James W., Nickerson, Cheryl A., Ott, C. Mark, Ramamurthy, Rajee, Pierson, Duane L.
Microgravity, Microbiological research

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Novel quantitative biosystem for modeling physiological fluid shear stress on cells

Article Abstract:

The development of a novel model system to mathematically model the fluid shear within a modified rotating wall vessel (RWV) bioreactor to evaluate the response of plantonic cultures of Salmonella enterica serovar Typhimurium to quantified ranges of physiological fluid shear is reported.

author: Wilson, James W., Nickerson, Cheryl A., Nauman, Eric A., Ott, Mark C., Sander, Ed, Tucker, Don L., Pierson, Duane
Physiological aspects, Genetic research, Salmonella enteritidis

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Cloning and transfer of the Salmonella pathogenicity island 2 type III secretion system for studies of a range of gram-negative genera

Article Abstract:

The expression of the cloned Salmonella pathogenicity island 2 (SPI-2) system in different Gammaproteobacteria and Alphaproteobacteria dependent on the bacterial strain and growth medium is reported. This could offer a desired function to an engineered gram-negative strain.

author: Wilson, James W., Nickerson, Cheryl A., Coleman, Clint
Gram-negative bacteria, Salmonella, Bacterial transformation

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subjects list: Research, Genetic aspects