A recombinant, fully human monoclonal antibody with antitumor activity constructed from phage-displayed antibody fragments
Article Abstract:
University researchers from Germany and the Netherlands isolated an antibody fragment specific for the Ep-CAM tumor molecule and converted it into a human monoclonal antibody.
author: Logtenberg, Ton, Huls, Gerwin A., Heijnen, Ingmar A.F.M., Cuomo, Maria E., Koningsberger, Jacob C., Wiegman, Luus, Boel, Edwin, Van der Vuurst de Vries, Anne-Renee, Loyson, Sabine A.J., Helfrich, Wijnand, Van Berge Henegouwen, Gerard P., Van Meijer, Marja, De Kruif, John
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 1999
Netherlands, Brief Article
Selective enhancement of gene transfer by steroid-medicated gene delivery
Article Abstract:
Researchers in Switzerland have devised a new method of inserting genetic material into cells using steroid-mediated gene delivery.
author: Rebuffat, Alexandre et al
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2001
Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display
Article Abstract:
Researchers in Switzerland and Germany used ribosome display techniques to select and mutate single-chain antibody fragments.
author: Hanes, Jozef, Schaffitzel, Christiane, Knappik, Achim, Pluckthun, Andraes
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2000
subjects list: Germany, Antibodies, Switzerland, Genetic engineering